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What is Acid Peptic Disease?

May 2, 2017

What is acid peptic disease?

Acid peptic disease – commonly called APD – includes a number of conditions. All these conditions are the result of damage from acid and peptic activity in gastric secretions. APD occurs when the acid starts irritating the inner cells (mucosal layer) of the stomach. Acid peptic diseases mostly affect the oesophagus, stomach, and duodenum.

What causes acid peptic disease?

Acid peptic diseases are caused by the excessive presence of acid and pepsin. The two main types of acid peptic diseases are gastric and duodenal ulcer. However, they can also occur at the GJ Stoma, lower end of oesophagus, and Meckel’s diverticulum. According to duration and complexity of symptoms they can be acute or chronic.

What are the symptoms of acid peptic disease?

A digestive function disorder, acid peptic disease is characterised by dyspepsia (discomfort, heartburn, or nausea). However, the classic symptom of peptic ulcer disease, is defined as pain centered in the upper abdomen or discomfort
characterised by fullness, bloating, distention, or nausea. Factors contributing to acid peptic disorder Acid peptic disorder results when the balance between the aggressive and defensive factors in the gastroduodenal mucosa is disrupted. This balance could be disrupted by factors such as H pylori infection, NSAID (Non-steroidal anti-inflammatory drug), and acid secretory abnormalities. A defect in bicarbonate production and acid neutralisation in the duodenal bulb is also a potent cause.

Factors that lead to acid peptic disorder

  • Smoking
  • Alcohol
    NSAIDs including aspirin
  • Foods
    • Citrus or acidic fruits
    • Chocolate, caffeine, and alcohol
    • Greasy, fatty, spicy, and fried foods
    • Garlic, onions, and mint flavourings
  • Drugs, such as aspirin and types of steroids
  • Helicobacter pylori

Factors that minimise the effects of acid peptic disorder

  • Successful treatment of H pylori infections decreases the risk of several APDs such as peptic ulcers, MALToma, and possibly gastric cancers.
  • PPI (Proton Pump Inhibitor) therapy reduces the recurrence of peptic ulcer bleeding in patients taking NSAIDs and aspirin.

What is the treatment for acid peptic disease?

Only your physician can decipher the best treatment suited for you. However, the most common types of treatment are:

  • Antacids. These serve as quick-relief solutions. However, they are not effective as long term treatment.
  • H2 receptor blockers. These are more effective than the antacids.
  • Proton pump blockers. These can completely abolish the secretion of acid.
  • Eradication of Hpylori. Treatment of H pylori minimises the chances of suffering from several types of APDs.

At Fortis Hospitals, we care for your well being. We strongly recommend practicing prevention and securing health. In a world where lifestyle evolves by the day, it is essential to stay in the pink of health. Wishing you and your family good health and happiness always.
The information in the booklet is not intended as a substitute for medical advice but it is to be used as aid in understanding ailment. Always consult your doctor about your medical condition.


Posted in Gastro Care